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WHO Classification of Tumours
WHO Classification of Tumours of the Digestive System
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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010





C21 - Anus and anal canal:
 
The number attached to each tumour is the ICD-O morphology code of the International Classification of Diseases for Oncology (ICD-O) [1] and the Systematized Nomenclature of Medicine (http://snomed.org).
/0 benign tumours
/1 unspecified, borderline or uncertain behaviour
/2 in situ carcinomas
/3 malignant tumours.

1. Fritz A, Percy C, Jack A, Shanmuragatnam K, Sobin LH, Parkin DM, Whelan S (Eds) International Classification of Diseases for Oncology. World Health Organization: Geneva 2000





Epithelial tumors
    Premalignant lesions
        8077/0 Squamous intraepithelial neoplasia, low grade
        8077/2 Squamous intraepithelial neoplasia (dysplasia), high grade

    Bowen disease
        8542/3 Paget disease, extramammary

    Carcinoma
        8070/3 Squamous cell carcinoma, NOS
        8051/3 Verrucous carcinoma, NOS
        8020/3 Undifferentiated carcinoma
        8140/3 Adenocarcinoma, NOS
        8480/3 Mucinous adenocarcinoma
        8090/3 Basal cell carcinoma, NOS

    Neuroendocrine neoplasms
        8240/3 Neuroendocrine tumor G1 (NET G1) / Carcinoid
        8249/3 Neuroendocrine tumor G2 (NET G2)
        8246/3 Neuroendocrine carcinoma, NOS
            8013/3 Large cell neuroendocrine carcinoma
            8041/3 Small cell neuroendocrine carcinoma
        8244/3 Mixed adenoneuroendocrine carcinoma

Other tumours
    8720/3 Melanoma, NOS
    8052/0 Squamous cell papilloma, NOS
    8405/0 Papillary hidradenoma
     Fibroepithelial polyp
     Inflammatory cloacagenic polyp

Secondary tumours
    Secondary tumours of the anal canal