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WHO Classification of Tumours
Secondary tumours of the appendix

Secondary tumours are unusual in the appendix. Primary sites include carcinomas of the gastrointestinal and urogenital tract, breast, lung, and gallbladder. Metastatic thymoma and melanoma have also been reported
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Azuma M, Sunagawa M, Shida S (1994)
[Metastatic carcinoma of the appendix].
Nihon Rinsho Suppl 6: 725-7

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Gembala RB, Hare JL, Meilahn J (1993)
Intraabdominal metastatic thymoma.
AJR Am J Roentgenol 161: 1331

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Gopez EV, Mourelatos Z, Rosato EF, Livolsi VA (1997)
Acute appendicitis secondary to metastatic bronchogenic adenocarcinoma.
Am Surg 63: 778-80

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Rose PG, Abdul-Karim FW (1997)
Isolated appendiceal metastasis in early ovarian carcinoma.
J Surg Oncol 64: 246-7

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Stein A, Sova Y, Almalah I, Lurie A (1996)
The appendix as a metastatic target for male urogenital tumours.
Br J Urol 78: 647-8

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Wolf C, Friedl P, Obrist P, Ensinger C, Gritsch W (1999)
Metastasis to the appendix: sonographic appearance and review of the literature.
J Ultrasound Med 18: 23-5

. A common pattern is serosal involvement, presumably due to trans - coelomic spread. Endometriosis involving the appendix wall may mimic metastatic adenocarcinoma
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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010


Norman J. Carr
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Norman J. Carr
School of Medicine
University of Southampton

Leslie H. Sobin
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Leslie H. Sobin
Department of Hepatic and of Gastrointestinal Pathology
Armed Forces Institute of Pathology (AFIP)