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WHO Classification of Tumours
Early lesions: plasmacytic hyperplasia (PH) and infectious mononucleosis (IM)-like PTLD
Tumours of haematopoietic and lymphoid tissues


Definition

The early lesions are defined as lymphoid proliferations in an allograft recipient, characterized by architectural preservation of the involved tissue, with preservation of the nodal sinuses or tonsillar crypts, and residual or sometimes floridly reactive follicles in some cases. In most cases, they form mass lesions. These lesions should be distinguished from lymphoid proliferations with other known explanations or other non-specific chronic inflammatory processes. Cases that have florid follicular hyperplasia but which do not fit into the PH or IM-like categories have been separately designated by some authors.

> Related topics
Introduction: Post-transplant lymphoproliferative disorders (PTLD)
Introduction: Classification of lymphoid neoplasms