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WHO Classification of Tumours
Inflammatory cloacagenic polyp
Anus and anal canal


Definition

Inflammatory cloacagenic polyps, first described in 1981
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Lobert PF, Appelman HD (1981)
Inflammatory cloacogenic polyp. A unique inflammatory lesion of the anal transitional zone.
Am J Surg Pathol 5: 761-6



, are commonly associated with mucosal prolapse and sometimes with haemorrhoids
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Chetty R, Bhathal PS, Slavin JL (1993)
Prolapse-induced inflammatory polyps of the colorectum and anal transitional zone.
Histopathology 23: 63-7




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Levey JM, Banner B, Darrah J, Bonkovsky HL (1994)
Inflammatory cloacogenic polyp: three cases and literature review.
Am J Gastroenterol 89: 438-41



. These polyps arise in the anal transitional zone (ATZ) and form a rounded or irregular mass measuring 15 cm in diameter. Histologically, the polyp consists of hyperplastic rectal mucosa, partly covered with ATZ-type or squamous epithelium. The surface is typically eroded and the stroma shows oedema, vascular ectasia, inflammatory cells and granulation tissue. Vertically oriented smooth-muscle fibres are found between the elongated and tortuous crypts. It can be confused with a prolapsed rectal adenoma
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Parfitt JR, Shepherd NA (2008)
Polypoid mucosal prolapse complicating low rectal adenomas: beware the inflammatory cloacogenic polyp!
Histopathology 53: 91-6




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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



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Topographic definition of the anal canal, anal margin and perianal region