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WHO Classification of Tumours
Squamous cell papilloma, NOS
Anus and anal canal


A benign epithelial neoplasm characterized by a papillary growth pattern and a proliferation of neoplastic squamous cells without morphologic evidence of malignancy. Most frequently it arises in the oral cavity, nasopharynx, larynx, esophagus, vagina, and vulva.

Squamous cell papilloma of the anal canal
Rarely, papillomatous processes covered by normal, more or less keratinized squamous epithelium can be found in the anus. Such lesions should be tested for the presence of human papillomavirus (HPV). Lesions that are negative for HPV are commonly regarded as “burned-out” condylomas

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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010


Topographic definition of the anal canal, anal margin and perianal region