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WHO Classification of Tumours
Serrated polyposis
Colon and rectum


Definition

Historically, serrated polyposis has been called hyperplastic polyposis; however, the term “serrated polyposis” is preferred, given the common presence of sessile serrated adenoma/polyp (SSA/P) in this process
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Torlakovic E, Snover DC (1996)
Serrated adenomatous polyposis in humans.
Gastroenterology 110: 748-55



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Differing criteria to define serrated polyposis have been suggested, although all are empirical and the described categories may represent different diseases. Definitions include: (1) at least five serrated polyps proximal to the sigmoid colon with two or more of these being > 10 mm; (2) any number of serrated polyps proximal to the sigmoid colon in an individual who has a first-degree relative with serrated polyposis; or (3) > 20 serrated polyps of any size, but distributed throughout the colon

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Hamilton SR, Aaltonen LA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Digestive System.
3rd Edition
IARC Press: Lyon 2000




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Rashid A, Houlihan PS, Booker S, Petersen GM, Giardiello FM, Hamilton SR (2000)
Phenotypic and molecular characteristics of hyperplastic polyposis.
Gastroenterology 119: 323-32




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Jass JR (2007)
Gastrointestinal polyposes: clinical, pathological and molecular features.
Gastroenterol Clin North Am 36: 927-46, viii




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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



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