Glandular intraepithelial neoplasia, low grade
The incidence of small-intestinal adenocarcinoma is increased in patients with chronic inflammatory conditions affecting the small bowel, such as Crohn disease and coeliac disease
Green PHR , Stavropoulos SN, Panagi SG, Goldstein SL, Mcmahon DJ, Absan H, Neugut AI (2001)
Characteristics of adult celiac disease in the USA: results of a national survey.
Am J Gastroenterol 96: 126-31
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Risk of intestinal cancer in inflammatory bowel disease: a population-based study from olmsted county, Minnesota.
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Crohn's disease and cancer risk (Denmark).
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Adenocarcinoma complicating Crohn's disease.
Dis Colon Rectum 36: 654-61
Rampertab SD, Forde KA, Green PH (2003)
. In patients with Crohn disease, invasive adenocarcinoma is preceded by intraepithelial neoplasia or dysplasia, which may appear either flat or polypoid endoscopically. In one study, dysplasia was identified adjacent to 75% of Crohn disease-associated small- intestinal adenocarcinomas
Small bowel neoplasia in coeliac disease.
Gut 52: 1211-4
Sigel JE, Petras RE, Lashner BA, Fazio VW, Goldblum JR (1999)
. Histologically, the dysplasia seen in the small bowel appears similar to inflammatory bowel disease associated colonic dysplasia and is classified as low grade and high grade according to the degree of cellular dysplasia
Intestinal adenocarcinoma in Crohn's disease: a report of 30 cases with a focus on coexisting dysplasia.
Am J Surg Pathol 23: 651-5
Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
International Agency for Research on Cancer: Lyon 2010
Commentary: Preneoplastic lesions of the digestive system