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WHO Classification of Tumours
Capillary hemangioma
Liver and intrahepatic bile ducts


Definition

A common hemangioma characterized by the presence of capillary-sized vascular channels without prominent epithelioid endothelial cells.

Hepatic capillary hemangioma or infantile haemangioma (formerly often designated as infantile haemangioendothelioma) is a benign vascular tumour similar to capillary haemangioma of the skin in infancy. It is the most common mesenchymal tumour of the liver in infants and children, accounting for about 20% of all liver tumours arising between birth and age 21 years. The clinically significant cases usually present in the first 2 years of life, when infantile haemangioma represents 40% of all tumours and 70% of benign tumours

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Stocker J, Askin F
Pathology of Solid Tumors in Children.
Chapman & Hall: London 1998



. It occurs more frequently in females (63%) than in males. Patients usually present with an enlarging abdomen, some may develop congestive heart failure or consumption coagulopathy
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Dehner LP, Ishak KG (1971)
Vascular tumors of the liver in infants and children. A study of 30 cases and review of the literature.
Arch Pathol 92: 101-11




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Selby DM, Stocker JT, Waclawiw MA, Hitchcock CL, Ishak KG (1994)
Infantile hemangioendothelioma of the liver.
Hepatology 20: 39-45



, and about 10% have haemangiomas in the skin or other sites. There may be a variety of associated congenital anomalies, including hemihypertrophy and Cornelia de Lange syndrome
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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



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