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WHO Classification of Tumours
Cribriform comedo-type adenocarcinoma
Colon and rectum


Definition

This rare tumour has extensive large cribriform glands with central necrosis analogous to breast adenocarcinomas and is usually microsatellite-stable with CpG island hypermethylation
Click to access Pubmed
Chirieac LR, Shen L, Catalano PJ, Issa JP, Hamilton SR (2005)
Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation.
Am J Surg Pathol 29: 429-36




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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



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