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WHO Classification of Tumours
Verruca vulgaris
Skin


Definition

Verrucas or condyloma are common, benign, contagious epithelial tumours caused by infection with human papillomaviruses (HPV).

Verruca vulgaris (common wart) occurs predominantly in children and adolescents. Clinically detectable cutaneous verrucae develop from a few weeks to 18 months after inoculation. Common warts are typically associated with HPV-2, occasionally with HPV-1, HPV-4 and HPV-7. Histologically, they show marked hyperkeratosis and acanthosis. Koilocytes (large vacuolated cells with small pyknotic nuclei) are present in the upper Malpighian layer and in the granular layer

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LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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