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WHO Classification of Tumours
PUVA keratosis


PUVA keratosis arises in response to a photochemotherapy employing a Psoralen product in association with long-wave ultraviolet radiation (UVA). PUVA is mainly used in the treatment of psoriasis. Long-term treatment is associated with an increased risk for development of actinic keratoses and squamous cell carcinoma. PUVA keratoses appear to have less keratinocytic atypia than sunlight-induced actinic keratoses
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LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005