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WHO Classification of Tumours
Langerhans cell histiocytosis
Tumours of haematopoietic and lymphoid tissues


Langerhans cell histiocytosis (LCH) is a clonal neoplastic proliferation of Langerhans-type cells that express CD1a, langerin and S100 protein, and shows Birbeck granules by ultrastructural examination.

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Langerhans cell sarcoma
Introduction: Histiocytic and dendritic cell neoplasms