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WHO Classification of Tumours
SÚzary syndrome
Tumours of haematopoietic and lymphoid tissues


Definition

SÚzary syndrome (SS) is defined by the triad of erythroderma, generalized lymphadenopathy and the presence of clonally related neoplastic T-cells with cerebriform nuclei (SÚzary cells) in skin, lymph nodes and peripheral blood (PB). In addition, one or more of the following criteria are required: an absolute SÚzary cell count of at least 1000 cells per mm3, an expanded CD4+ T-cell population resulting in a CD4/CD8 ratio of more than 10 and/or loss of one or more T-cell antigens.

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