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WHO Classification of Tumours
Enteropathy-associated T-cell lymphoma
Tumours of haematopoietic and lymphoid tissues


Definition

Enteropathy-associated T-cell lymphoma (EATL) is an intestinal tumour of intra­epithelial T lymphocytes, showing varying degrees of transformation but usually presenting as a tumour composed of large lymphoid cells, often with an inflammatory background. The adjacent small intestinal mucosa shows villous atrophy with crypt hyperplasia. In 10−20% of cases, the lymphoma is composed of monomorphic medium-sized cells. This monomorphic variant (type II EATL) may occur sporadically, without risk factors for coeliac disease (Table 11.03).


> Related Topics
Introduction: Classification of lymphoid neoplasms