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WHO Classification of Tumours
Lymphomatoid granulomatosis
Tumours of haematopoietic and lymphoid tissues


Definition

Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive lymphoproliferative disease involving extra­nodal sites, composed of Epstein-Barr virus (EBV)-positive B cells admixed with reactive T cells, which usually predominate. The lesion has a spectrum of histological grade and clinical aggressiveness, which is related to the proportion of large B cells.

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Introduction: Classification of lymphoid neoplasms