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WHO Classification of Tumours
Superficial fibromatoses (palmar/plantar)
Connective, subcutaneous and other soft tissues


Definition

Superficial fibromatoses are fibroblastic proliferations arising in the palmar or plantar soft tissues. The tumours consist of small nodules that infiltrate the aponeurosis and subcutaneous fat. Histologically, they are characterized by plump, immature-appearing spindle shaped cells, moderate amounts of collagen, and elongated vessels. Older lesions are less cellular and more densely collagenous.
Palmar fibromatosis mainly occurs in adults of Caucasian origin with a rapid increase in incidence with advancing age and a distinct male predominance. In contrast, plantar lesions arise much more frequently in children and adolescents. The predilection for males is less pronounced than in palmar lesions. 5-20% of patients with palmar fibromatoses also have plantar lesions. Superficial fibromatoses tend to recur locally, but they do not metastasize

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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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