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WHO Classification of Tumours
Primary cutaneous gamma-delta T-cell lymphoma
Tumours of haematopoietic and lymphoid tissues


Definition

Primary cutaneous γδ T-cell lymphoma (PCGD-TCL) is a lymphoma composed of a clonal proliferation of mature, activated γδ T-cells with a cytotoxic phenotype. This group includes cases previously known as subcutaneous panniculitis-like T-cell lymphoma (SPTCL) with a γδ phenotype. A possibly related condition may present primarily in mucosal sites. Whether cutaneous and mucosal γδ TCL are all part of a single disease, i.e. muco-cutaneous γδ TCL, is not yet clear
Click to access Pubmed
Jaffe ES, Krenacs L, Raffeld M (2003)
Classification of cytotoxic T-cell and natural killer cell lymphomas.
Semin Hematol 40: 175-84




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Wolf T, Brodt HR, Fichtlscherer S, Mantzsch K, Hoelzer D, Helm EB, Mitrou PS, Chow KU (2005)
Changing incidence and prognostic factors of survival in AIDS-related non-Hodgkin's lymphoma in the era of highly active antiretroviral therapy (HAART).
Leuk Lymphoma 46: 207-15



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> Related Topics
Introduction: Primary cutaneous peripheral T-cell lymphomas, rare subtypes
Subcutaneous panniculitis-like T-cell lymphoma
Introduction: Classification of lymphoid neoplasms