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WHO Classification of Tumours
Plasma cell leukaemia
Tumours of haematopoietic and lymphoid tissues


Definition

An aggressive plasma cell neoplasm with usually short survival. It is characterized by the presence of neoplastic plasma cells in the peripheral blood. The peripheral blood plasma cells comprise more than 20% of the peripheral blood white cells. It may be the initial presentation of a plasma cell neoplasm or manifest as a terminal complication of plasma cell myeloma. Lymphadenopathy and organomegaly are frequent clinical signs, whereas bone pain and osteolytic lesions are less frequently present.

> Related Topics
Definition: Plasma cell neoplasms
Introduction: Classification of lymphoid neoplasms