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WHO Classification of Tumours
B lymphoblastic leukaemia/lymphoma with t(5;14)(q31;q32) IL3-IGH
Tumours of haematopoietic and lymphoid tissues


Definition

A neoplasm of lymphoblasts committed to the B lineage in which the blasts harbour a translocation between the IL3 gene and the IGH@ gene, resulting in a variable eosino­philia. This diagnosis may be made based on immunophenotypic and genetic findings even if the bone marrow (BM) blast count is low.

> Related Topics
B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities.
Introduction: Classification of lymphoid neoplasms