Mast cell sarcoma
Tumours of haematopoietic and lymphoid tissues
Mast cell sarcoma is extremely rare and characterized by a localized and destructive growth of highly atypical mast cells, which can be identified only after application of appropriate immunohistochemical markers, particularly anti-tryptase and anti-CD117. Although initially localized, distant spread followed by a terminal phase resembling mast cell leukaemia
(MCL) is seen after a short interval. Mast cell sarcomas have been reported to occur in the larynx, large bowel, meninges, bone and skin
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Mast-cell sarcoma of the tibia.
J Clin Pathol 60: 424-5
Horny HP, Parwaresch MR, Kaiserling E, Müller K, Olbermann M, Mainzer K, Lennert K (1986)
Mast cell sarcoma of the larynx.
J Clin Pathol 39: 596-602
Kojima M, Nakamura S, Itoh H, Ohno Y, Masawa N, Joshita T, Suchi T (1999)
Mast cell sarcoma with tissue eosinophilia arising in the ascending colon.
Mod Pathol 12: 739-43