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WHO Classification of Tumours
Hydroa vacciniforme-like lymphoma
Skin


Definition

Hydroa vacciniforme-like lymphoma is an EBV-positive cutaneous T-cell lymphoma occurring in children, and associated with sensitivity to insect bites and sun sensitivity
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Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (Eds.)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
4th Edition
International Agency for Research on Cancer: Lyon 2008



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This condition is seen mainly in children and adolescents from Asia, or in Native Americans from Central and South America, and Mexico. Like other EBV-positive T-cell and NK-cell lymphomas, predisposition for this condition may be related to a defective cytotoxic immune response to EBV.