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WHO Classification of Tumours
Pituicytoma
Pituitary gland


Definition

Pituicytoma is a rare, slowly growing glial spindle cell glial neoplasm of adults that originates in the neurohypophysis or infundibulum
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Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Eds.)
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007



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The clinical course is benign and curative surgery is possible. No instances of malignant transformation or distant metastasis have been reported.
Histopathoplogically, pituicytomas show elongate, bipolar spindle cells arranged in interlacing or storiform pattern and express vimentin, S-100 protein and, to a variable degree, GFAP

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Brat DJ, Scheithauer BW, Staugaitis SM, Holtzman RN, Morgello S, Burger PC (2000)
Pituicytoma: a distinctive low-grade glioma of the neurohypophysis.
Am J Surg Pathol 24: 362-8




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Ulm AJ, Yachnis AT, Brat DJ, Rhoton AL (2004)
Pituicytoma: report of two cases and clues regarding histogenesis.
Neurosurgery 54: 753-7; discussion 757-8



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