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WHO Classification of Tumours
Angioimmunoblastic T-cell lymphoma
Tumours of haematopoietic and lymphoid tissues


Definition

Angioimmunoblastic T-cell lymphoma (AITL) is a peripheral T-cell lymphoma characterized by systemic disease, a polymorphous infiltrate involving lymph nodes, with a prominent proliferation of high endothelial venules and follicular dendritic cells.

> Synonyms and historical annotation
AITL was previously felt to be an atypical reactive process, angioimmunoblastic lymphadenopathy, with an increased risk of progression to lymphoma. Currently, overwhelming evidence suggests that AITL rises de novo as a peripheral T-cell lymphoma

Click to access Pubmed
Dogan A, Attygalle AD, Kyriakou C (2003)
Angioimmunoblastic T-cell lymphoma.
Br J Haematol 121: 681-91



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> Related Topics
Peripheral T-cell lymphoma, (NOS)
Introduction: Classification of lymphoid neoplasms