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WHO Classification of Tumours
Burkitt lymphoma
Tumours of haematopoietic and lymphoid tissues


Definition

Burkitt lymphoma (BL) is a B-cell lymphoma with an extremely short doubling time that often presents in extranodal sites or as an acute leukaemia. It is composed of monomorphic medium-sized transformed cells. Translocation involving MYC is highly characteristic but not specific. No single parameter (such as morphology, genetic analysis or immunophenotyping) can be used as the gold standard for the diagnosis of BL, but a combination of several diagnostic techniques is necessary.

> Related Topics
B-cell lymphoma, unclassifiable with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma
Introduction: Classification of lymphoid neoplasms