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WHO Classification of Tumours
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
Tumours of haematopoietic and lymphoid tissues


Definition

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an extranodal lymphoma composed of morphologically hetero­geneous small B-cells including marginal zone (centrocyte-like) cells, cells resembling monocytoid cells, small lymphocytes, and scattered immunoblasts and centro­blast-like cells. There is plasma cell differentiation in a proportion of the cases. The infiltrate is in the marginal zone of reactive B-cell follicles and extends into the interfollicular region. In epithelial tissues, the neoplastic cells typically infiltrate the epithelium forming lymphoepithelial lesions
Click to access Pubmed
Isaacson PG, Du MQ (2004)
MALT lymphoma: from morphology to molecules.
Nat Rev Cancer 4: 644-53



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> Related Topics
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Nodal marginal zone lymphoma
Introduction: Classification of lymphoid neoplasms