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WHO Classification of Tumours
Angiosarcoma
Adrenal gland


Definition

Angiosarcoma is a malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma.
Angiosarcomas in the adrenal gland are usually of the epithelioid type

Click to access Pubmed
Henry JF, Sebag F, Iacobone M, Hubbard J, Maweja S (2002)
[Lessons learned from 274 laparoscopic adrenalectomies].
Ann Chir 127: 512-9




Click to access Pubmed
Wenig BM, Abbondanzo SL, Heffess CS (1994)
Epithelioid angiosarcoma of the adrenal glands. A clinicopathologic study of nine cases with a discussion of the implications of finding "epithelial-specific" markers.
Am J Surg Pathol 18: 62-73



and have a variable prognosis
Click to access Pubmed
Wenig BM, Abbondanzo SL, Heffess CS (1994)
Epithelioid angiosarcoma of the adrenal glands. A clinicopathologic study of nine cases with a discussion of the implications of finding "epithelial-specific" markers.
Am J Surg Pathol 18: 62-73



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