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WHO Classification of Tumours
Ganglioneuroma
Adrenal gland


Definition

Ganglioneuroma is a benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood.

It typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray.
Ganglioneuroma features also observed in composite phaeochromocytomas or paragangliomas.