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WHO Classification of Tumours
Mucinous adenocarcinoma
Thyroid gland


An invasive adenocarcinoma composed of malignant glandular cells which contain intracytoplasmic mucin. Often, the infiltrating glandular structures are associated with mucoid stromal formation. The histological hallmark of mucinous carcinoma is the presence of abundant mucoid lakes around strands or clusters of tumour cells that usually show large regular nuclei and prominent nucleoli
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Ronald A. DeLellis, Ricardo V. Lloyd, Philipp U. Heitz, Charis Eng
World Health Organization Classification of Tumours. Pathology and Genetics of Tumors of Endocrine Organs
IARC Press: Lyon 2004


Mucinous carcinoma of the thyroid is very rare, with only a few cases reported

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Diaz-Perez R, Quiroz H, Nishiyama RH (1976)
Primary mucinous adenocarcinoma of thyroid gland.
Cancer 38: 1323-5

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Sobrinho-Simões M, Stenwig AE, Nesland JM, Holm R, Johannessen JV (1986)
A mucinous carcinoma of the thyroid.
Pathol Res Pract 181: 464-71

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Sobrinho-Simões MA, Nesland JM, Johannessen JV (1985)
A mucin-producing tumor in the thyroid gland.
Ultrastruct Pathol 9: 277-81