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WHO Classification of Tumours
Synovial sarcoma, NOS
Kidney


Definition

A malignant mesenchymal neoplasm characterized by the chromosomal translocation t(X;18)(p11;q11). It mainly affects young adults, more commonly males. The vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Histologically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur and may metastasize to the lungs, bones, and lymph nodes
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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Renal synovial sarcoma (SS) is a spindle cell neoplasm that rarely displays epithelial differentiation. Most tumours are solid, but can contain areas of haemorrhage, necrosis and cyst formation

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Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



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