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WHO Classification of Tumours
Angiosarcoma
Kidney


Definition

Hemangiosarcoma is a malignant tumour arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by vascular anastomosing and branching channels. The malignant cells lining the vascular channels are spindle shaped or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma
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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Primary renal angiosarcomas are exceedingly rare. They affect adults (mean age 58 years), with a strong male predominance (ratio 19:4). The prognosis is poor, due to rapid development of haematogenous metastasis. The mean survival is approximately 8 months

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Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



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