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WHO Classification of Tumours
Chromophobe cell renal carcinoma
Kidney


Definition

Chromophobe renal cell carcinoma (CRCC) accounts for approximately 5% of renal cell tumours and is histologically characterized by large pale or eosinophilic cells with prominent cell membranes
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Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



. It affects mainly adults and is usually confined to the renal parenchyma. Invasive growth and metastatic spread are rare. CRCC occurs in the setting of the inherited Birt-Hogg-Dubé (BHD) syndrome .