logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Osteosarcoma, NOS
Kidney


Definition

Osteosarcoma is a usually aggressive, malignant bone-forming mesenchymal tumour, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom
Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



. It may metastasize to other anatomic sites, particularly the lungs.

Primary renal osteosarcoma is exceedingly rare (<20 cases reported). Compared with osteosarcoma of bone, it affects older patients (>40 years of age). Tumours consist of spindle and multinucleated giant cells which produce neoplastic osteoid and bone. Prognosis of primary renal osteosarcoma is very poor

Click for details
Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



.