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WHO Classification of Tumours
Choriocarcinoma, NOS
Prostate gland


Definition

An aggressive malignant tumour arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Histopathologically, choriocarcinomas consist of an admixture of syncytiotrophoblast, cytotrophoblast, and intermediate trophoblast, typically with haemorrhage, necrosis and vascular invasion
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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



. There is often a marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas tend to disseminate through the hematogenous route.