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WHO Classification of Tumours
Mixed cell adenocarcinoma
Corpus uteri


Definition

Mixed adenocarcinoma of the uterine corpus is a tumour arising from the endometrium. It is composed of malignant glandular epithelial cells and consists of a mixture of a type I (estrogen-dependent, endometrioid or mucinous ) and a type II (non-estrogen-dependent, serous or clear cell ) adenocarcinoma (the minor type must amount to at least 10% of the total tumour volume).
Mixed adenocarcinomas with a type II tumour fraction of 25% or more have a poor prognosis

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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