Malignant melanoma is a malignant, usually aggressive tumour composed of atypical, neoplastic melanocytes. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain
LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
IARC Press: Lyon 2005
Histologic subtypes of malignant melanoma include:
Superficial spreading melanoma
Acral lentiginous melanoma
Lentigo maligna melanoma
Malignant melanoma of the cervix is very rare. The tumours are usually polypoid or fungating, pigmented masses. Approximately 50% of cases contain a junctional component. Spindle-shaped cells are frequently present.
The tumour arises in adults. Patients typically present with abnormal vaginal bleeding. The prognosis is dismal
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
IARC Press: Lyon 2003