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WHO Classification of Tumours
Carcinosarcoma, NOS
Cervix uteri


Definition

Carcinosarcoma is a malignant tumour composed of a mixture of carcinomatous and sarcomatous elements. Genetic analyses indicate that these are monoclonal tumours with divergent lines of differentiation.

Cervical carcinosarcomas may occur in all age groups, but most commonly arise in postmenopausal women. Patients typically present with abnormal uterine bleeding. The tumours are aggressive, the usual treatment is radical hysterctomy followed by chemotherapy and/or radiotherapy. Small tumours with a polypoid appearance may have a better prognosis

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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