logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Undifferentiated sarcoma
Cervix uteri


Definition

Undifferentiated endocervical sarcomas are polypoid or infiltrative tumours lacking specific differentiation. The neoplastic cells are spindle- or stellate-shaped and characterized by ill defined borders, scanty cytoplasm, hyperchromatic nuclei, nuclear atypia, and a markedly increased mitotic activity. They are arranged in a sheet-like, fasciculated or storiform pattern. The tumour contains areas of haemorrhage, necrosis, and myxoid degeneration.
Undifferentiated endocervical sarcomas affect adults. Patients typically present with vaginal bleeding or discharge. The prognosis is poor

Click for details
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



.