Leiomyosarcoma is an uncommon, aggressive malignant smooth muscle neoplasm, histologically characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid leiomyosarcoma
, myxoid leiomyosarcoma
, granular cell and inflammatory leiomyosarcoma
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
IARC Press: Lyon 2002
Leiomyosarcoma is the most common primary cervical sarcoma. It forms either a mass replacing and expanding the cervix or a polypoid growth. Areas of necrosis or haemorrhage are common. The tumour arises in adults. Patients typically present with vaginal bleeding or discharge. The prognosis is poor
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
IARC Press: Lyon 2003