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WHO Classification of Tumours
Leiomyosarcoma, NOS
Cervix uteri


Definition

Leiomyosarcoma is an uncommon, aggressive malignant smooth muscle neoplasm, histologically characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid leiomyosarcoma , myxoid leiomyosarcoma , granular cell and inflammatory leiomyosarcoma
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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Leiomyosarcoma is the most common primary cervical sarcoma. It forms either a mass replacing and expanding the cervix or a polypoid growth. Areas of necrosis or haemorrhage are common. The tumour arises in adults. Patients typically present with vaginal bleeding or discharge. The prognosis is poor

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003