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WHO Classification of Tumours
Villous adenocarcinoma
Cervix uteri


Definition

Villous adenocarcinoma of the cervix is a variant of mucinous adenocarcinoma characterized by a frond-like pattern. The papillae and glands are typically lined by one to several layers of columnar cells, some of which contain mucin. The epithelium is usually moderately to well differentiated. There are scattered mitoses. The invasive part of the tumour typically consists of elongated branching glands separated by fibrous stroma.
Cervical villous adenocarcinoma generally arises in young women. Lymph node metastasis is rare

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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