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WHO Classification of Tumours
Adenocarcinoma, NOS
Cervix uteri


Definition

A common, malignant tumour characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreted product (e.g., mucinous, serous).
Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell adenocarcinoma, hepatocellular carcinoma, colon adenocarcinoma, and prostate adenocarcinoma.

Approximately 50% of cervical adenocarcinomas are exophytic, polypoid or papillary masses. Other tumours are nodular with diffuse enlargement or ulceration of the cervix. Tumours that deeply infiltrate the wall produce a barrel-shaped cervix. About 15% of patients have no visible lesion

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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> Early invasive (microinvasive) adenocarcinoma is characterized by minimal stromal invasion. The risk of local lymph node metastasis is negligible, the prognosis is excellent

Click for details
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003