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WHO Classification of Tumours
Squamous cell carcinoma, large cell, nonkeratinizing, NOS
Cervix uteri


Definition

Non-keratinizing squamous cell carcinoma is a histological variant of squamous cell carcinoma composed of large atypical cells, without morphologic evidence of keratin production (keratinization may be present in individual cells, but there are no keratin pearls). The cells are solitary or arranged in syncytia and have large nuclei with anisokaryosis
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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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