A non-invasice, benign neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated. The neoplastic epithelial cells may or may not display moderate cellular atypia or dysplasia.
Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract.
In the vulva, adenomas are rare. They are composed of clusters of small, closely packed glands and tubules lined by columnar to cuboidal mucinous epithelium
Tavassoli FA, Devilee P (Eds.)
. Two subtypes are distinguished:
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
IARC Press: Lyon 2003
> Bartholin gland adenoma: The neoplastic structures are contiguous with Bartholin gland elements. Bartholin gland adenoma associated with adenoid cystic carcinoma
has been reported
Koenig C, Tavassoli FA (1998)
Nodular hyperplasia, adenoma, and adenomyoma of Bartholin's gland.
Int J Gynecol Pathol 17: 289-94
> Adenoma of minor vestibular glands: There are no intervening Bartholin duct elements associated with the lesion
Axe S, Parmley T, Woodruff JD, Hlopak B (1986)
Adenomas in minor vestibular glands.
Obstet Gynecol 68: 16-8