Invasive papillary carcinoma
Invasive micropapillary carcinoma of the breast is a rare variant of invasive ductal carcinoma
composed of small clusters of neoplastic cells lying within prominent stromal spaces resembling dilated vascular channels. The neoplastic cells form papillary structures. Nuclear pleomorphism is moderate, mitoses are infrequent. The tumour typically presents as a solid, lobulated mass. Necrosis is absent, and there is no lymphocytic reaction.
Invasive micropapillary carcinomas affect predominantly women >40 years of age. The micropapillary growth pattern is correlated with vascular invasion and axillary lymph node metastases
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IARC Press: Lyon 2003