Lipoma is the most common soft tissue tumour. It is composed of mature white adipocytes without atypia
Fletcher CDM, Unni KK, Mertens F (Eds.)
. The tumour usually presents as a slowly growing, well circumscribed, solitary mass measuring <5 cm in diameter. Histologically, lipomas are not markedly different from the surrounding adipose tissue. Fibrosis or myxoid changes may be present. Impaired blood supply or trauma may result in secondary alterations such as lipogranulomas, lipid cysts, and calcifications.
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
IARC Press: Lyon 2002
The following variants of lipoma occur in the breast:
- Spindle cell lipoma
Lew WY (1993)
Spindle cell lipoma of the breast: a case report and literature review.
Diagn Cytopathol 9: 434-7
Marsh WL, Lucas JG, Olsen J (1989)
Chondrolipoma of the breast.
Arch Pathol Lab Med 113: 369-71
Intramammary lipomas are rare, the lesions are more frequently localized subcutaneously. Patients are usually 40-60 years old. Surgical resection is usually curative
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
IARC Press: Lyon 2003