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WHO Classification of Tumours
Lipoma, NOS
Breast


Definition

Lipoma is the most common soft tissue tumour. It is composed of mature white adipocytes without atypia
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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



. The tumour usually presents as a slowly growing, well circumscribed, solitary mass measuring <5 cm in diameter. Histologically, lipomas are not markedly different from the surrounding adipose tissue. Fibrosis or myxoid changes may be present. Impaired blood supply or trauma may result in secondary alterations such as lipogranulomas, lipid cysts, and calcifications.

The following variants of lipoma occur in the breast:
- Angiolipoma
- Spindle cell lipoma

Click to access Pubmed
Lew WY (1993)
Spindle cell lipoma of the breast: a case report and literature review.
Diagn Cytopathol 9: 434-7




- Hibernoma
- Chondrolipoma

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Marsh WL, Lucas JG, Olsen J (1989)
Chondrolipoma of the breast.
Arch Pathol Lab Med 113: 369-71





Intramammary lipomas are rare, the lesions are more frequently localized subcutaneously. Patients are usually 40-60 years old. Surgical resection is usually curative

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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