logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Pleomorphic adenoma
Breast


Definition

Pleomorphic adenoma is a neoplasm characterized by the presence of benign epithelial and myoepithelial cells and a mesenchymal component that may contain mucoid, myxoid, cartilaginous, or osseous areas. It may be completely or partially encapsulated. It usually presents as a slowly growing painless mass. It may recur after excision or transform to a malignant carcinoma ex pleomorphic adenoma .

Pleomorphic adenoma of the breast is rare. It occurs over a wide range of age and affects predominantly women. Multiple lesions have been reported

Click to access Pubmed
Ballance WA, Ro JY, el-Naggar AK, Grignon DJ, Ayala AG, Romsdahl MG (1990)
Pleomorphic adenoma (benign mixed tumor) of the breast. An immunohistochemical, flow cytometric, and ultrastructural study and review of the literature.
Am J Clin Pathol 93: 795-801




Click to access Pubmed
Chen KT (1990)
Pleomorphic adenoma of the breast.
Am J Clin Pathol 93: 792-4



. Because of its chondroid stromal component, the lesion may be misinterpreted as a malignant tumour
Click for details
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



.