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WHO Classification of Tumours
Tubular adenoma, NOS


Tubular adenoma of the breast is a benign, compact proliferation of small, round tubular structures composed of epithelial and myoepithelial cell layers. The epithelial cells may show apocrine or lactating features, but are otherwise similar to those of the normal resting breast. Mitoses are usually infrequent. The tubular lumina may contain eosinophilic proteinaceous material, but are often empty. The stroma is scanty and may contain a few lymphocytes. Tubular adenomas typically appear as round, firm, well defined, slowly growing nodules.
Tubular adenomas of the breast predominantly affect young women. They are rare before menarche and after menopause. The lesion does not predispose to carcinoma. Complete excision is curative

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003