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WHO Classification of Tumours
Sebaceous adenocarcinoma


Sebaceous adenocarcinoma of the breast is a rare epithelial tumour characterized by sebaceous differentiation. The lobulated or nested proliferations of sebaceous cells are surrounded by smaller ovoid to spindle-shaped cells. Focal squamous morules may be present. The tumour presents as a sharply delineated mass measuring 7.5 to 20 cm. There are only very few reported cases of sebaceous adenocarcinoma of the breast. Patients were women between 45 and 62 years of age. All of them presented with a painless, palpable mass. Distant metastases may occur
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Varga Z, Kolb SA, Flury R, Burkhard R, Caduff R (2000)
Sebaceous carcinoma of the breast.
Pathol Int 50: 63-6

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003

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