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WHO Classification of Tumours
Invasive papillary carcinoma
Breast


Definition

Invasive papillary carcinoma is a rare breast adenocarcinoma characterized by the presence of an intraductal and an invasive capillary carcinomatous component. Microscopically, expansile invasive papillary carcinomas are typically circumscribed and show delicate or blunt papillae and focal solid areas of tumour growth. Tumour stroma is usually not abundant. Occasionally, prominent extracellular mucin production is found. More than 75% of invasive papillary carcinomas are associated with ductal carcinoma in situ (DCIS).
Invasive papillary carcinoma accounts for less than 2% of invasive breast carcinomas, affects predominantly postmenopausal women and usually carries a favourable prognosis

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Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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