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WHO Classification of Tumours
Adult rhabdomyoma
Connective, subcutaneous and other soft tissues


Adult rhabdomyoma (A-RM) is a rare benign mesenchymal neoplasm arising from skeletal muscle, characterized by the presence of neoplastic large cells with clear cytoplasm and spider cells. 90% of cases arise in the head and neck region, especially in the upper aerodigestive mucosa and in soft tissue of the neck. The lesions are unencapsulated but well circumscribed, nodular or lobulated masses and range in size from 1.5 to 7.5 cm.
Adult rhabdomyoma affects adults (median age: 60 years) and shows a 3:1 predilection for males. The recommended treatment is complete surgical excision. A-RM has a tendency to recur but lacks malignant potential

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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002