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WHO Classification of Tumours
Glomus tumor, malignant
Connective, subcutaneous and other soft tissues


Definition

Malignant glomus tumour is an exceedingly rare morphologic variant of glomus tumour with a size >2 cm. The tumour arises in subfascial or visceral tissues and is histopathologically characterized by the presence of atypical mitotic figures, or marked nuclear atypia, or a combination of both. Malignant glomus tumours are highly aggressive. Approximately 40% of cases metastasize, resulting in the death of the patient
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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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